Tuesday, June 27, 2017

[NASA HQ News] NASA Celebrates International Asteroid Day with Special Broadcast

  June 27, 2017 
MEDIA ADVISORY M17-077
NASA Celebrates International Asteroid Day with Special Broadcast

NASA will mark the worldwide observance of International Asteroid Day at noon EDT Friday, June 30, with a special television program featuring the agency's Planetary Defense Coordination Office and other projects working to find and study near-Earth objects (NEOs). The program will air on NASA Television and the agency's website.

Viewers will learn how NASA-funded researchers find, track and characterize NEOs – asteroids and comets that come within the vicinity of Earth's orbit and could pose an impact hazard to Earth – and how NASA is working to get our nation prepared to respond to a potential impact threat.

The program will include segments on NASA's NEO projects from multiple locations, including the agency's Headquarters in Washington and Jet Propulsion Laboratory (JPL) in Pasadena, California. Viewers may submit questions during the program using #AskNASA.

The broadcast will be part of a 24-hour Asteroid Day program from Broadcasting Center Europe, beginning at 9 p.m. June 29 (1 a.m. June 30 GMT) and streaming online at:

https://asteroidday.org/live

"At NASA, every day is an asteroid day, but we value the international collaboration for a designated day to call attention to the importance of detecting and tracking hazardous asteroids," said Planetary Defense Officer Lindley Johnson at NASA Headquarters.

NASA's Planetary Defense Coordination Office is responsible for finding, tracking and characterizing potentially hazardous asteroids and comets coming near Earth, issuing warnings about possible impacts, and assisting coordination of U.S. government response planning, should there be an actual impact threat.

For more information visit:

https://www.nasa.gov/planetarydefense

For asteroid news and updates, follow AsteroidWatch on Twitter:

https://www.twitter.com/AsteroidWatch

-end-

 

Press Contacts

Laurie Cantillo / Dwayne Brown
Headquarters, Washington
202-358-1077 / 202-358-1726
laura.l.cantillo@nasa.gov / dwayne.c.brown@nasa.gov

Guy Webster / DC Agle
Jet Propulsion Laboratory, Pasadena, Calif.
818-354-6278 / 818-393-9011
guy.webster@jpl.nasa.gov / agle@jpl.nasa.gov 
 

NASA news releases and other information are available automatically by sending an e-mail message with the subject line subscribe to hqnews-request@newsletters.nasa.gov.
To unsubscribe from the list, send an e-mail message with the subject line unsubscribe to hqnews-request@newsletters.nasa.gov.

 

 

Nature Neuroscience Contents: July 2017 Volume 20 Number 7, pp 897 - 1033

If you are unable to see the message below, click here to view.
Nature Neuroscience

TABLE OF CONTENTS

July 2017 Volume 20, Issue 7

News and Views
Articles
Technical Report
Erratum
Corrigenda
Addendum
Advertisement
 

"Pain-free" Drug Discovery starts here

Charles River offers comprehensive pain drug discovery resources using relevant in vitro ion channel assays and specific in vivo rodent models that validated using established and novel readouts. Learn more about how our multi-modal validation services can be applied to available and novel models of various types of pain.


Subscribe
 
Facebook
 
RSS
 
Recommend to library
 
Twitter
 
Advertisement
npj Molecular Phenomics is an online-only, open access journal that provides a forum for cutting-edge scientific advances in the emerging field of phenomics, the study of the physical and chemical characteristics of an individual in quantitative terms.

Part of the Nature Partner Journals series, npj Molecular Phenomics is published in partnership with Fudan University. The journal is now open for submissions. 

Find out more >>>
 

News and Views

Top

A checkpoint to pain   pp897 - 899
Michael Hirth, Jagadeesh Gandla and Rohini Kuner
doi:10.1038/nn.4586
The checkpoint pathway consisting of programmed death ligand 1 (PD-L1) and its receptor, PD-1, modulates immune function in cancer and infection, but unexpectedly, it also silences pain signals in nerves.

See also: Article by Chen et al.

Direction selectivity starts early   pp899 - 901
Qi Fang and Huizhong W Tao
doi:10.1038/nn.4585
Disruption of retinal direction selectivity reveals both peripheral and central computations contributing to direction selectivity in mouse visual cortex. These mechanisms work together to better encode motion directions and speeds.

See also: Article by Hillier et al.

The thalamic paradox   pp901 - 902
László Acsády
doi:10.1038/nn.4583
Most thalamic research has focused on sensory transmission. Now three independent groups reveal the thalamus to be critical in behaviors linked to frontal cortex and the maintenance of persistent cortical activity during delays.

See also: Article by Bolkan et al.

Sampling memory to make profitable choices   pp903 - 904
Brice A Kuhl and Nicole M Long
doi:10.1038/nn.4588
A computational model explains how memories of past rewards guide value-based choices. Incorporating behavioral and functional MRI evidence, the findings indicate that 'sampling' from individual memories of past rewards influences choices.

See also: Article by Bornstein & Norman

Neuroscience
JOBS of the week
Multiple Opportunities in Molecular Neuroscience
Loyola University Chicago - Stritch School of Medicine
Post-Doc in Neuroscience
State University of New York
Postdoctoral Fellow in Interneuron Development
National Institute of Child Health and Human Development (NICHD)
Post-Doctoral Fellowship : Bethesda, MD, United States
National Institutes of Health (NIH)
MSWA Senior Research Fellow in Brain Plasticity
Perron Institute
More Science jobs from
Neuroscience
EVENT
The Neuroscience of Obesity
17.09.17
Siena, Italy
More science events from
Advertisement
Open for Submissions

An interdisciplinary journal dedicated to publishing high-quality open research relevant to all aspects of schizophrenia and psychosis.

Explore the benefits of submitting your next research article.
 

Articles

Top

Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy   pp905 - 916
Emily V Fletcher, Christian M Simon, John G Pagiazitis, Joshua I Chalif, Aleksandra Vukojicic et al.
doi:10.1038/nn.4561
The authors show that in a mouse model of spinal muscular atrophy (SMA), there is a reduction in sensory synaptic drive that leads to motor neuron dysfunction and motor behavior impairments. SMA motor neurons showed a lower surface expression of Kv2.1 potassium channels and reduced spiking ability. Increasing neuronal activity pharmacologically led to the normalization of Kv2.1 surface expression and an improvement in motor function.

PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1   pp917 - 926
Gang Chen, Yong Ho Kim, Hui Li, Hao Luo, Da-Lu Liu et al.
doi:10.1038/nn.4571
The authors identify programmed cell death ligand-1 (PD-L1), an immunity suppressor produced by cancer cells, as a new pain inhibitor and a neuromodulator. They report that PD-L1 is produced by melanoma and normal neural tissues and that it inhibits acute and chronic pain. Via activation of PD-1, its receptor, PD-L1 decreases the excitability of nociceptive neurons in mouse and human dorsal root ganglia.

See also: News and Views by Hirth et al.

The cellular mechanism for water detection in the mammalian taste system   pp927 - 933
Dhruv Zocchi, Gunther Wennemuth and Yuki Oka
doi:10.1038/nn.4575
The authors find that mammalian acid-sensing taste receptor cells, previously shown to be putative sour taste sensors, also mediate responses to water. Optogenetic activation of this population of cells in thirsty mice induced robust drinking response in the absence of water. This study shows that acid-sensing TRCs contribute to the detection of water in the oral cavity.

Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus   pp934 - 942
Carlos A Campos, Anna J Bowen, Sung Han, Brent E Wisse, Richard D Palmiter et al.
doi:10.1038/nn.4574
Most cancer patients experience loss of appetite and feelings of illness, which contribute to cancer-related deaths and morbidity. The authors demonstrate that, in mice, activation of a subset of neurons in the parabrachial nucleus mediate cancer-induced anorexia and associated sickness behaviors.

A cerebellum-like circuit in the auditory system cancels responses to self-generated sounds   pp943 - 950
Shobhit Singla, Conor Dempsey, Richard Warren, Armen G Enikolopov and Nathaniel B Sawtell
doi:10.1038/nn.4567
The authors provide evidence that a cerebellum-like structure at the initial stage of mammalian auditory processing (the dorsal cochlear nucleus) functions to cancel out self-generated sounds. A similar function has been established for cerebellum-like structures in electroreceptive fish, suggesting a conserved function for these structures across vertebrates.

Cortical gamma band synchronization through somatostatin interneurons   pp951 - 959
Julia Veit, Richard Hakim, Monika P Jadi, Terrence J Sejnowski and Hillel Adesnik
doi:10.1038/nn.4562
The authors establish a critical role for somatostatin interneurons in visually induced gamma oscillations in the primary visual cortex of mice. Optogenetic manipulations in awake animals, combined with an innovative computational model with multiple interneuron subtypes, provide a mechanism for the synchronization of neural firing across the retinotopic map.

Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex   pp960 - 968
Daniel Hillier, Michele Fiscella, Antonia Drinnenberg, Stuart Trenholm, Santiago B Rompani et al.
doi:10.1038/nn.4566
The authors monitored neuronal activity in mouse visual cortex during visual-motion stimulation and perturbed retinal direction selectivity. After perturbation, the proportion of posterior-motion-preferring cortical cells decreased, and their response at higher stimulus speeds was reduced. Thus, functionally distinct, retina-dependent and retina-independent computations of visual motion exist in mouse cortex.

See also: News and Views by Fang & Tao

Attention-related changes in correlated neuronal activity arise from normalization mechanisms   pp969 - 977
Bram-Ernst Verhoef and John H R Maunsell
doi:10.1038/nn.4572
Attention changes correlations between neuronal responses. In this study, Verhoef and Maunsell use multielectrode recordings in monkeys to reveal a link between normalization mechanisms, correlated neuronal activity and attention. The findings show that normalization mechanisms shape response correlations and that these correlations change when attention biases normalization mechanisms.

Identification of a motor-to-auditory pathway important for vocal learning   pp978 - 986
Todd F Roberts, Erin Hisey, Masashi Tanaka, Matthew G Kearney, Gaurav Chattree et al.
doi:10.1038/nn.4563
Although vocal learning is widely speculated to depend on motor to auditory (i.e., forward) pathways, the neurons that convey forward signals important to vocal learning remain unknown. Here the authors identify neurons that transmit signals from songbird motor to auditory regions and demonstrate their role in vocal learning.

Thalamic projections sustain prefrontal activity during working memory maintenance   pp987 - 996
Scott S Bolkan, Joseph M Stujenske, Sebastien Parnaudeau, Timothy J Spellman, Caroline Rauffenbart et al.
doi:10.1038/nn.4568
Using pathway-specific optogenetic inhibition, the authors demonstrate that projections from the mediodorsal thalamus to prefrontal cortex support the maintenance of working memory, while prefrontal-thalamic projections support subsequent choice selection. Thalamo-prefrontal projections have a circuit-specific role in sustaining prefrontal delay-period activity, a neuronal signature required for successful task performance.

See also: News and Views by Acsády

Reinstated episodic context guides sampling-based decisions for reward   pp997 - 1003
Aaron M Bornstein and Kenneth A Norman
doi:10.1038/nn.4573
The authors demonstrate that decisions for reward can have more a complicated dependence on past experiences than previously believed. Previous models describe decisions as influenced by rewards received in similar situations. Here the authors show that experiences that share only incidental features can also reemerge to bias present choices.

See also: News and Views by Kuhl & Long

Rich cell-type-specific network topology in neocortical microcircuitry   pp1004 - 1013
Eyal Gal, Michael London, Amir Globerson, Srikanth Ramaswamy, Michael W Reimann et al.
doi:10.1038/nn.4576
To unravel structural regularities in neocortical networks, Gal et al. analyzed a biologically constrained model of a neocortical microcircuit. Using extended graph theory, they found multiple cell-type-specific wiring features, including small-word and rich-club topologies that might contribute to the large repertoire of computations performed by the neocortex.

Flexible information routing by transient synchrony   pp1014 - 1022
Agostina Palmigiano, Theo Geisel, Fred Wolf and Demian Battaglia
doi:10.1038/nn.4569
Brain function relies on flexible communication between cortical regions. It has been proposed that changing patterns of oscillatory coherence underlie information routing. However, oscillations in vivo are very irregular. This study shows that short-lived and stochastic oscillatory bursts coordinate across areas to selectively modulate interareal communication.

Advertisement
Nature Awards for Mentoring in Science — Spain

Your mentor could win €10,000

Nominations are now open
 

Technical Report

Top

A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging   pp1023 - 1032
Eyiyemisi C Damisah, Robert A Hill, Lei Tong, Katie N Murray and Jaime Grutzendler
doi:10.1038/nn.4564
No techniques exist for the precise identification of vascular pericytes. Here the authors identify and characterize a fluorescent dye that exclusively labels pericytes. Using this tool for intravital imaging of the mouse brain, the authors provide conclusive evidence that these cells are molecularly and functionally distinct from all other brain and vascular cells.

Addendum

Top

Addendum: A viral strategy for targeting and manipulating interneurons across vertebrate species   p1033
Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi et al.
doi:10.1038/nn0717-1033d

Corrigenda

Top

Corrigendum: Opportunities and challenges in modeling human brain disorders in transgenic primates   p1033
Charles Jennings, Rogier Landman, Yang Zhou, Jitendra Sharma, Julia Hyman et al.
doi:10.1038/nn0717-1033b

Corrigendum: A viral strategy for targeting and manipulating interneurons across vertebrate species   p1033
Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi et al.
doi:10.1038/nn0717-1033c

Erratum

Top

Erratum: Infantile amnesia reflects a developmental critical period for hippocampal learning   p1033
Alessio Travaglia, Reto Bisaz, Eric S Sweet, Robert D Blitzer and Cristina M Alberini
doi:10.1038/nn0717-1033a

Top
nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.
Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com
More Nature Events

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount
(You will need to log in to be recognised as a nature.com registrant)

For further technical assistance, please contact our registration department

For print subscription enquiries, please contact our subscription department

For other enquiries, please contact our customer feedback department

Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Springer Nature's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne
San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW.

© 2017 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.

Springer Nature